Proteomic assessment of human, periodontal ligament fibroblasts, gingival fibroblasts and alveolar bone osteoblasts
نویسندگان
چکیده
منابع مشابه
Functional characteristics of gingival and periodontal ligament fibroblasts.
In periodontal surgery, healing after guided tissue regeneration (GTR) may be explained by differences in functional activities of gingival and periodontal ligament fibroblasts (GF and PDLF). Several studies in vitro have supported this hypothesis, but much remains to be defined. In the present work, gingival and periodontal ligament fibroblasts derived from five healthy subjects were isolated ...
متن کاملSemaphorin profiling of periodontal fibroblasts and osteoblasts.
UNLABELLED Cells of the periodontal attachment (cementoblasts, osteoblasts, and periodontal ligament fibroblasts) are descended from a common progenitor (the cranial neural crest). During their differentiation into different cell types, these cells separate from one another to form a laminated structure. Semaphorins (and their neuropilins and plexin receptors) act as cell guidance molecules for...
متن کاملRole of HMGB1 in proliferation and migration of human gingival and periodontal ligament fibroblasts.
High mobility group box 1 (HMGB1) was originally defined as a nuclear protein. However, later studies showed that HMGB1 was released from damaged cells into the extracellular milieu and functioned as a danger signaling molecule. HMGB1 has also been shown to exert proliferative and chemoattractant effects on many cell types. In this study, we investigated the in vitro effect of human recombinant...
متن کاملA comparative study of human periodontal ligament cells and gingival fibroblasts in vitro.
Both periodontal ligament and gingival tissue are thought to harbor cells with the ability to stimulate periodontal regeneration, i.e., formation of new bone, cementum, and connective tissue attachment. To understand further the role of these cells in the regenerative process, we compared human periodontal ligament cells and gingival fibroblasts, both derived from the same patient, same passage...
متن کاملActivity of 25-Hydroxylase in Human Gingival Fibroblasts and Periodontal Ligament Cells
BACKGROUND We previously demonstrated that 25-hydroxyvitamin D(3) concentrations in gingival crevicular fluid are 300 times higher than those in the plasma of patients with aggressive periodontitis. Here we explored whether 25-hydroxyvitamin D(3) can be synthesized by periodontal soft tissue cells. We also investigated which of the two main kinds of hydroxylases, CYP27A1 and CYP2R1, is the key ...
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ژورنال
عنوان ژورنال: Australian Dental Journal
سال: 2007
ISSN: 0045-0421
DOI: 10.1111/j.1834-7819.2007.tb06146.x